Here's how the clinical trial industry would approach baking the best bread. The bake shop owner would send out a job posting for a baker but wouldn’t tell them what type of bread they’d be baking. The fastest baker to respond would be hired. After they were hired, the baker would be informed that they... Continue Reading →
The perception of importance drives actions in clinical trials. Sponsors must work on creating positive perceptions by demonstrating site value and emphasizing study significance. A compelling story and direct sponsor-site connection elevate a study's importance. To engage sites effectively, consider involving them early, sharing the study's narrative, and treating them as valued partners.
Clinical trial sites play a crucial role in research, but are often overlooked. Higher site engagement can boost study performance. Involving sites early, seeking their input, and establishing site relationship teams can improve collaboration and motivation. Treating sites as valuable team members, not subordinates, benefits the entire trial. This approach ultimately leads to better study enrollment.
Clinical trial sites are burdened by pass-through costs, which are not fully reimbursed, leading to financial strain. The process of invoicing for these costs is time-consuming and often results in delayed or unreceived payments, causing additional administrative and financing expenses for the site. This impacts the site's operations, staff resources, and overall financial well-being.
Effective clinical trial recruitment is marred by a lack of prioritization. Despite considerable investments, the pivotal steps often slip through the cracks. Fostering a culture that gives due diligence to connecting suitable candidates with study teams is essential.
Clinical trial invoicing can be optimized with early invoicing, adherence to contract specifications, building relationships, setting reminders, and persistence. Deviating from contract instructions can lead to delayed payments.
It's time for clinical trial sponsors and CROs to recognize that sites should be compensated for monitoring visits. Sites are increasingly asked to do more in clinical trials and the study budgets haven't increased with the additional responsibilities.
Completing a feasibility questionnaire for a clinical trial is a critical process on the path to site selection. Take the proper steps to turn the feasibility questionnaire into selection for a study.
A significant factor in recruitment for participants and conduct of clinical trials is Principal Investigator / Site motivation. A motivated investigator can motivate study staff and increase recruitment potential for a trial and decrease site related issues. Conversely, an Investigator or clinical trial site that is not motivated or loses motivation during a trial can result in recruitment slowing or completely halting. It is not uncommon for sites to silently quit studies they were once excited about. This series of articles will examine the 4 I’s of Investigator / site motivation and unpack what can be done to optimize clinical trial conditions.
Clinical Research 