The last post in this series focused on the Impediments in clinical research that affect Investigator Motivation and ultimately, Momentum in a clinical trial. Those impediments obviously can be irritants, but there are many other things that result in site irritation. Don’t underestimate the effect that irritations can have on a clinical study and the reaction that can result from sites.
When you’re out for a walk and a single raindrop falls, you might not think too much of it or change your path. If the volume picks up and becomes a deluge, you’re going to react (at least I hope you do). Investigator Motivation decreases in a clinical trial long before the irritations become a storm.